Responsibility features of multiprofile assistance organization specialists (on the example of Sistema-112 operators) with different job satisfaction level have been considered. The direct comparison of groups of specialists with low, average, and high job satisfaction on separate scales of the OTV-70 questionnaire has been carried out, and interrelations among OTV-70 scales, I.G. Senin’s questionnaire of terminal values, and E.V. Kharitonova’s questionnaire of socio-professional demand for personality, as well as S.R. Pantileev’s methodology of self-relationship research have been revealed. It has been shown that operators with low job satisfaction in comparison with their colleagues with average and high levels more superficially understand the essence and significance of responsibility in the life of a human and society, less often do tasks, receive less positive emotions while doing it, are less eager to do it out of the desire to be a part of their team, and are less interested in the tasks result both for others and for themselves. In the correlative pleiad, the system-forming element in them is the emotional component of responsibility. In operators with average job satisfaction the responsibility components are correlated with the subjective professional demand indicators, in operators with high level - with negative self-esteem and subjective professional demand indicators.